The impact of Solifenacin on mental health: What you should know

The impact of Solifenacin on mental health: What you should know May, 12 2023

Introduction to Solifenacin

Solifenacin is a medication that is primarily used to treat overactive bladder symptoms. These symptoms include the frequent and urgent need to urinate, as well as incontinence. While it is quite effective in managing these issues, there have been some concerns about the impact of Solifenacin on mental health. In this article, we will explore the various ways in which this medication can affect your mental well-being and discuss what you should know when considering taking this drug.

Understanding How Solifenacin Works

To better understand the impact of Solifenacin on mental health, it's important to know how the drug works. Solifenacin belongs to a class of drugs called antimuscarinics, which work by blocking the muscarinic receptors in the bladder. This helps to relax the bladder muscles and reduce the frequency and urgency of urination. Although this medication is mainly targeted at the urinary system, it can also cross the blood-brain barrier and affect the central nervous system, potentially leading to mental health issues.

Potential Side Effects on Cognitive Function

One of the most significant ways in which Solifenacin can impact mental health is through its potential effects on cognitive function. Some studies have shown that antimuscarinic drugs, including Solifenacin, can cause cognitive impairment in certain individuals, especially older adults. This can manifest as memory problems, difficulty concentrating, and confusion. If you notice any of these symptoms while taking Solifenacin, it's important to discuss them with your healthcare provider to determine if a change in medication is necessary.

Anxiety and Depression

Another possible mental health issue that can arise from taking Solifenacin is an increase in anxiety and depression. While this is not a common side effect, some individuals may experience these symptoms as a result of changes in their brain chemistry. If you have a history of anxiety or depression, it's essential to monitor your mental health while taking Solifenacin and discuss any concerns with your healthcare provider.

Interactions with Other Medications

The impact of Solifenacin on mental health may also be influenced by interactions with other medications. Some drugs, such as antidepressants or antipsychotics, can increase the risk of cognitive impairment when taken together with Solifenacin. It's crucial to inform your healthcare provider of all the medications you are currently taking so they can assess potential interactions and adjust your treatment plan accordingly.

Considerations for Older Adults

As previously mentioned, older adults are at a higher risk of experiencing cognitive side effects from Solifenacin. This is due to age-related changes in the brain and a decreased ability to metabolize medications. If you are an older adult considering taking Solifenacin, it's essential to weigh the potential benefits and risks with your healthcare provider and carefully monitor your mental health while on the medication.

Managing Mental Health Side Effects

If you experience mental health side effects while taking Solifenacin, there are several steps you can take to manage these symptoms. First, discuss your concerns with your healthcare provider. They may recommend adjusting your dosage, changing medications or prescribing additional treatments to help manage your symptoms. Additionally, engaging in regular exercise, practicing relaxation techniques, and maintaining a healthy diet can all contribute to improved mental health while taking Solifenacin.

When to Seek Professional Help

If you are experiencing severe or persistent mental health issues while taking Solifenacin, it's important to seek professional help. Reach out to your healthcare provider to discuss your symptoms and determine the best course of action. In some cases, a referral to a mental health professional may be necessary for further evaluation and treatment.


Although Solifenacin can be an effective treatment for overactive bladder symptoms, it's essential to be aware of the potential impact on mental health. By understanding the possible side effects, monitoring your mental health, and seeking professional help when necessary, you can ensure that you are making the best decisions for your overall well-being. Remember, it's crucial to discuss any concerns or questions with your healthcare provider to ensure that Solifenacin is the right choice for you.